Epithelial Stem Cell Research Takes a Step in Hair Cloning

One of the two major components of the human hair follicle, epithelial stem cells, were converted successfully in a lab from adult cells recently. The study was led by Dr. Xiaowei “George” Xu, PHD and associate professor of Pathology and Laboratory of Medicine and Dermatology, and his team at Perelman School of Medicine at the University of Pennsylvania. The team included researchers from University of Pennsylvania’s departments of Biology and Dermatology, as well as New Jersey Institute of Technology.

Human Hair Follicle Growth on Mice 

Xu and his team have been working on epithelial component of the hair follicle, admitting that there was difficulty in the past producing the required amount until their recent discovery. When the team injected epithelial stem cells in immunocompromised mice, Xu discovered numerous signs of cell regeneration, mainly in hair follicles, and the stem cells created a structurally recognizable hair shaft. This raises the possibility of eventual hair regeneration in people.

When the epithelial stem cells were mixed with the follicular inductive dermal cells of mouse, and grafted onto the immunodeficient mice, the results actually showed growth of functional human epidermis and follicles structurally identical to human hair follicle.

Other Hair Component Still a Challenge 

While epithelial stem cells do aid in regeneration of cells and even wound healing, Xu acknowledges missing second major factor in hair regeneration – dermal papillae cells

When a person loses hair, they lose both types of cells. Xu explains. We have solved one major problem, the epithelial component of the hair follicle. We need to figure out a way to also make new dermal papillae cells, and no one has figured that part out yet.

Read more: http://www.uphs.upenn.edu/news/News_Releases/2014/01/xu/

New Technique Holds Promise for Hair Growth

Hair cloning continues to evade medical research by the limitations of the growth of specific cells called dermal papilla cells.When human dermal papilla cells are grown in culture, they lose the ability to grow hair.

The New York Times published an article describing the recent experience of researcher Angela Christiano and  researchers from Durham University in Britain.

They were able to grow dermal papilla cells in a new way.

Essentially they were able to grow dermal papilla cells by inverting the container which the cells would be typically grown in and were able to observe growth that could not be achieved before. It appeared that three dimensional contact between the cells resulted in the needed signals to begin hair growth.

This is another piece of a  large and complex puzzle on how hair grows. The Hair Regeneration System reflects how I have integrated some of the recent studies on the behavior of dermal papilla cells. Cells and signals which are critical to hair growth appears to be what we are restoring with the wound healing technology of ECM (extracellular matrix) by ACell and PRP (platelet rich plasma). Hopefully this research will reveal more specific factors which can be applied clinically in the future.

 Amiya Prasad, M.D.

Kim Kardashian Undergoes So Called “Vampire Facial”

kim kardashian vampire facelift

It’s the bloody secret Kim Kardashian is turning to in order stay beautiful and it isn’t for the faint of heart.

It’s being called the vampire facelift or the vampire facial. It promises younger, firmer-looking skin.

Kim underwent the procedure on the latest episode of Kourtney and Kim Take Miami. First, blood is taken from her arm, and then spun into a platelet-rich plasma.

The blood is then combined with a wrinkle-filler and then, the mixture is injected into the skin with tiny motorized needles.

It’s supposed to fill in fine lines and acne scars.

Kim tweeted a photo of what she looked like after the procedure and her face was a bloody mess. Some are even comparing it to the horror movie, Carrie.

And it’s not just Kim. Plenty of women looking for younger looking skin are undergoing the procedure.

Cosmetic surgeon, Dr. Amiya Prasad, says he performs four vampire facelifts a week at his office in Manhattan.

Dr. Prasad said, “You want to go deep if you want to generate more collagen more aggressively for problems such as fine-lines, wrinkles or sun damage.

The procedure takes about 45 minutes and Dr. Prasad says results can last for about six months.

Read more: http://www.insideedition.com/entertainment/5970-kim-kardashian-undergoes-so-called-vampire-facial

Kim Kardashian’s $1,500 ‘vampire facial’ is a Hollywood hit that promises younger, firmer-looking skin

 

kim kardashian 'vampire facial'

Kim Kardashian has a Vampire Facelift on camera for ‘KIm and Kourtney Take Miami.’

Keeping up with the Kardashians is getting bloody ridiculous.

Attention-starved Kim K tweeted a shot of her blood-spattered face after a vampire facial, the gruesome $1,500 treatment that promises younger, firmer-looking skin.

The Vampire Facelift – trademarked by Alabama doctor Charles Runels draws blood from the patient’s arm with a needle and separates the platelets into a platelet-rich plasma (PRP) using a centrifuge.

The plasma is then combined with Restylane or Juvederm, and then injected into the face to stimulate collagen production to create new skin and to remove fine lines and acne scars. The 45-minute Facelift is expected to be such a hit in Hollywood that a gift certificate for the painful procedure was included in this year’s Academy Awards swag bag.

PHOTOS: KEEPING UP WITH KIM KARDASHIAN

vampire facelift procedure

Beauty takes pain for Kim Kardashian.

Kanye West’s baby mama documented the spa session on the latest episode of “Kim and Kourtney Take Miami,” where she visits the Miami Institute for Age Management for the controversial treatment. “Ow, that hurts so bad!” cries the reality star in the clip as blood streams down her face.

The extreme reaction is because her treatment includes the invasive Dermapen, a device that uses nine tiny motorized needles to cause puncture wounds in the skin before applying the platelet-rich plasma mixure.

Plenty of New York women are willing to face the pain, however, for a chance to look younger. Cosmetic surgeon Amiya Prasad performs four Vampire Facelifts a week at his upper East Side practice.

“This is a more aggressive treatment than a regular facial,” says Prasad, who charges around $1,200 for a 45-minute blood facial, “but it’s justified because skin quality improves quite nicely.” He says typically clients notice results in a couple of days that last four to six months.

RELATED: KIM KARDASHIAN RUSHES TO DOCTOR AFTER PREGNANCY SCARE

kim kardashian ‘vampire facial’ procedure

Kim Kardashian didn’t take the facial quietly!

But you’ll want to wait a day or two before dinner parties or meeting small children since the Dermapen causes bleeding and swelling just like Kardashian’s beauty bloodbath.

“But as bad as your face may look on the day of the procedure, it’s remarkable how good people can look a couple of days later,” he says.

Some medi-spas claim that the reality star’s blood-soaked procedure was played up for the cameras.

“It’s completely absurd,” says Dr. Jack Berdy, the director of SmoothMED, a walk-in Botox boutique in midtown that also offers the Vampire Facelift. He uses less-invasive injections than the Dermapen seen in the video. “You inject it like you would any other filler,” he says. “You can do it on your lunch break.”

RELATED: KIM KARDASHIAN UNDERGOES BLOODY ‘VAMPIRE’ FACIAL

 

kim kardashian after vampire facelift procedure

Kardashian is supposed to have a ‘youthful’ look after undergoing the painful procedure.

Plus, Berdy points out that the plasma mixture on Kardashian’s face should be yellow not red. “Her procedure is not set in any sense of reality,” he scoffs.

Dr. Anthony P. Sclafani, the director of facial plastic surgery at the New York Eye and Ear Infirmary, explains the red smears all over Kardashian’s face could come from not separating the platelets completely.

“Maybe there’s still some blood in it,” suggests Sclafani, who’s done extensive research on the competing $1,500 Selphyl system. He also injects platelet-rich plasma for facial rejuvenation, but without mixing in the added fillers. It’s a simple injection, much like getting Botox or Restalyne. “No needle is fun, but most people are able to do this without any anesthesia,” he says. “They shouldn’t scream in pain like that.”

Even Prasad, who uses the Dermapen regularly, laughed after watching Kardashian’s onscreen procedure. “That looks pretty barbaric!” he says. “She’s a celebrity so, of course, she deals with everything very dramatically.”

He adds, “It can be done very, very gently, and I won’t let what happened to Kim Kardashian happen to you.”

By / NEW YORK DAILY NEWS

Read more: http://www.nydailynews.com/life-style/health/kim-kardashian-vampire-facelift-bloody-mess-article-1.1285646#ixzz2NOlISidJ

Prasad Medi Spa’s Fabulous Face Treatment

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Dr. Prasad speaks at The Aesthetic Show in Las Vegas about PRP and The Vampire Facelift

Dr. Prasad at The Aesthetic ShowSaturday, April 14, 2011 –

Dr. Prasad was a featured speaker at The Aesthetic Show at The Aria Hotel in Las Vegas on  to teach physicians about his techniques for performing PRP (platelet rich plasma) treatment and The Vampire Facelift. “I was impressed by the large number of people who attended the lectures and workshops,” comments Dr. Prasad. “I know from doing these procedures for a long time that people are very happy with using their own material to restore volume in the face and have glowing skin.”

Dr. Prasad discussed the benefits of an authentic Vampire Face-Lift Procedure as well as other Vampire PRP applications including combination PRP therapies as the future of autologous skin rejuvenation and repair.

Local Anesthesia Safer for Plastic Surgery Procedures and Benefits Recovery

By Amiya Prasad, M.D., FACS

Cosmetic procedures continue to grow in popularity, especially as new techniques and advancements are made in the field of plastic surgery. Before undergoing a cosmetic procedure, it is critical for patients to consider the surgeon’s anesthesia preference. The difference should make or break your decision. Today, most, if not all, cosmetic procedures can be performed under local anesthesia, however, many plastic surgeons continue to place patients under general anesthesia despite the increased risk for complications.

Dermatologic Surgery (February 2012) published a study based on ten years of data from Florida and six years of data from Alabama and found that more than two-thirds of deaths and three-quarters of hospital transfers were associated with cosmetic surgery performed under general anesthesia. Liposuction, one of the most common cosmetic procedures, accounted for 32 percent of cosmetic procedure-related deaths and 22 percent of all cosmetic procedure-related complications under general anesthesia. No deaths were associated with liposuction under local anesthesia.

General anesthesia vs. local anesthesia with sedation
When a patient is placed under general anesthesia, the patient is placed on a respirator and an endotracheal tube is placed in the throat to help them breathe. A combination of drugs causes a deep sleep during the procedure and paralyzes the body. Some patients prefer general anesthesia because they want to make sure that they are completely knocked out and unable to remember anything about the actual procedure.

Unfortunately, complication rates are much greater under general anesthesia and the body is put at a greater risk. Following a surgical procedure, patients often have a sore throat from the endotracheal tube, are very fatigued and more likely to feel nauseated or actually vomit. Recovery is considerably longer because the body has to recover from the surgery and the general anesthesia.

Under local anesthesia with sedation, a patient is placed under intravenous (IV) sedation and the area that will be operated on is numbed. The patient is relaxed, comfortable and virtually unaware of the procedure thanks to light medication, but the whole body is not paralyzed. Local anesthesia is a much safer alternative to general anesthesia because it does not put the body under stress in the same way. Most importantly, fewer drugs are needed so recovery from the procedure is faster.

Following a surgical procedure where local anesthesia is used, a patient can walk easily out of the office and does not have the nausea common with general anesthesia. Under local anesthesia, a surgical procedure becomes much less invasive and the risks to the body diminish significantly.

Local anesthesia – a much safer option
The most recent studies by leading anesthesiologists, such as Barry Friedberg, M.D., share the professional opinion that most, if not all cosmetic surgery procedures, can be performed safely under local anesthesia with intravenous sedation. Despite this fact, a large percentage of people undergoing cosmetic surgery are still subjected to the risks of general anesthesia.

The reason for this may be financial. General anesthesia requires less prep time and more procedures can be performed in a day. However, the longer someone is under general anesthesia, the more stress it puts on the heart and lungs. With local anesthesia, the preparation time is longer and fewer patients can be accommodated in a day. But, the bottom line is that a patient’s safety should always come first – far more important than the financial bottom line.

Prasad Cosmetic Surgery and Medi-Spa uses LITE anesthesia (Local, Intravenous, Tumescent, Ease of recovery) with great success for our patients. LITE is safer and allows for a much quicker and easier recovery.